Exosomes/Microvesicles: Heterogeneity, Biogenesis, Function, and Therapeutic Developments (E2)

Exosomes/Microvesicles: Heterogeneity, Biogenesis, Function, and Therapeutic Developments (E2) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held during Jun 04 - 08, 2018 at Beaver Run Resort & Conference Center, Breckenridge, Colorado, United States of America.

Extracellular vesicles (EVs) have emerged as critical mediators of intercellular communication in both local and distant microenvironments, during normal development and physiological processes, and in orchestrating systemic pathophysiological events. EVs comprise a large group of heterogeneous particles, including exosomes and microvesicles, and are released from virtually all cell types. Differing in size, macromolecular composition and mechanism of formation, subpopulations of extracellular vesicles contain biologically active molecules, such as nucleic acids (DNA, mRNA, microRNA and other noncoding RNAs), proteins (transmembrane receptors, transcription factors, enzymes, extracellular matrix proteins) and lipids that can in part or in sum contribute to the functional capabilities of the vesicle itself, or the reprogramming of target cells that interact with EVs.

Session Topics :

• Extracellular Vesicles (EVs): Cargo and Composition
• EVs and Regulation of the Immune Response
• EVs and Cancer I (Tumor Growth and Dissemination)
• EVs in Neurobiology: Neurodevelopment, Degeneration and Regeneration
• EVs and Cancer II (Metastases)
• Current and Emerging Technologies
• EVs in Host-Pathogen Interactions
• EV Therapeutics

Additional Details will be posted as soon as they are available.