Pharmacy and Medicine, Immunology and Microbiology
New York, New York, United States of America
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Andrea Schietinger is a Professor and Cancer Immunologist at the Memorial Sloan Kettering Cancer Center. She investigates immune responses to cancer, molecular mechanisms underlying tumor-induced T-cell dysfunction, and new approaches for cancer immunotherapy. Schietinger’s laboratory investigates the regulatory mechanisms of T-cell dysfunction in the context of tumors. They use transgenic mouse models to understand how T cell unresponsiveness in tumor-reactive T cells is molecularly and epigenetically regulated, to design strategies to override cell-intrinsic T cell dysfunction programs to improve cancer immunotherapy and to ultimately validate the findings and insights in human cancers through collaborations with clinical investigators.