Michael A. Nader PhD

Michael Nader, Ph.D., received his doctorate in experimental psychology from the University of Minnesota. He did his post-doctorate work at the Uniformed Services University of the Health Sciences in Bethesda, MD, where he was mentored by renowned drug researcher James Barrett, Ph.D. Subsequently, Nader was Research Faculty at the University of Chicago working in the laboratory of William L. Woolverton, Ph.D. Woolverton introduced Nader to the study of nonhuman primates including a monkey model for self-administration. In 1992 Nader joined the faculty at Wake Forest School of Medicine; he has spent over 30 years refining his nonhuman primate models for the study of substance abuse.

Specifically, Nader examines the relationships among drug addiction, impulsivity, cognitive function, and social/environmental factors in nonhuman primate models of human disease. Distinctive aspects of his research are self-administration and social housing; these characteristics allow him a deeper insight into addictive impulses and the impact of social behavior on drug abuse. His approach considers sex differences, social hierarchy, and drug history as important variables affecting the outcome, and he is concerned with the physiological consequences of chronic drug use.

Nader believes combining social behavior with drug self-administration is the best predictive model of human drug-taking. In addition, Nader partners with physicists and radiologists to observe how substances attach to brain receptors, and to conduct longitudinal studies observing the consequences of long-term drug abuse, recovery, and abstinence using the latest in brain imaging technology.

Nader’s discoveries are impacting the perception of drug abuse. Specifically, his research with socially-housed primates demonstrates the potential impact of social hierarchy on drug use and recovery. He advocates that drug abuse will manifest uniquely in different users and seeks diverse solutions to address this disease.