Nathan R.tref PhD

Dr. Treff is the Director for the REI division’s Molecular Genetics Basic Science Research Laboratory and an Associate Professor of Obstetrics and Gynecology at UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ. Dr. Treff’s background is in biochemistry, molecular biology, and genetics with an emphasis in reproductive and stem cell biology. He obtained his Ph.D. in Biochemistry from Washington State University and conducted postdoctoral fellowships at the University of Wisconsin-Madison and The Serono Reproductive Biology Institute.

The bulk of his research is in molecular genetics including genome-wide microarray analysis of gene expression and single nucleotide polymorphisms (SNP), chromatin immunoprecipitation, electrophoretic mobility shift, northern blot assays, quantitative real-time reverse transcriptase-polymerase chain reaction, short tandem repeat, and SNP genetic fingerprinting, protein-antibody array, western blot, ELISA, cloning and sequencing, protein and nucleic acid purification, single-cell whole-genome and transcriptome amplification, and systematic gene ontology analysis of gene expression.

Dr. Treff has a variety of research skills in cellular biology including embryonic stem cell culture and directed differentiation, magnetic-activated cell sorting, stable recombinant cell line transfection and selection, and conventional tissue culture of eukaryotic cell lines. Dr. Treff has developed and led a new molecular biology research team towards improving the treatment of infertility. His scientific contributions were acknowledged at the 2007 ASRM meeting in Washington, DC where the REI division received the “ASRM Prize Paper Award”. He is dedicated to education and advancement in reproductive medicine, and to facilitating basic and translational research using state-of-the-art molecular biology approaches.